Archives for 2012 (Vol-1, Issue-4) Journal of Pharmacognosy and Phytochemistry

Archives for 2012 (Vol-1, Issue-4)

Journal of Pharmacognosy and Phytochemistry

• Evaluation of Antimicrobial Activity of Crude Methanol Extract of Solanum nodiflorum Jacq (Solanaceae)
  Authored by Ibrahim T. Babalola* , Esther A. Adelakun, Sadiq Y. Garba(Nigeria)

• Recent Trends of Phytosomes for Delivering Herbal Extract with Improved Bioavailability
  Authored by Arijit Gandhi *, Avik Dutta, Avijit Pal, Paromita Bakshi (India)

• Isolation Of Crotepoxide From Berries of Croton Macrostachyus and Evaluation of Its Anti-Leishmanial Activity
  Authored by Habtamu Gelaw, Legesse Adane*, Yinebeb Tariku, Asrat Hailu (Ethiopia)

• A Review on Herbal Antioxidants
  Authored by Sangh Partap*, Sanjay pandey (India)

• In Vitro Anthelmintic Activity of Lagenaria Siceraria Leaves in Indian Adult Earthworm
  Authored by Amit Kumar*, Sangh Partap (India)

• An Overview on Traditional Medicinal Plants as Aphrodisiac Agent
  Authored by Ramandeep Singh*, Sarabjeet Singh, G. Jeyabalan , Ashraf Ali(India)

• Evaluation of Membrane Stabilizing Activity, Total Phenolic Content, Brine Shrimp Lethality Bioassay, Thrombolytic and Antimicrobial Activities of Tagetes patula L.
  Authored by Md. Ruhul Kuddus, Mirza Sonia Alam, Sharmin Reza Chowdhury, Farhana Rumi, Md. Al Amin Sikder, and Mohammad A. Rashid*(Bangladesh)

• The Lebanese Citrus Aurantium: A Promising Future in Medicinal Phytochemistry
  Authored by Salim Makhoul, Youssef Bakkour, Hanna El-Nakat*, Fawaz El Omar (Lebanon)

• Antioxidant and Cytotoxic Activities of Cuphea hyssopifolia Kunth (Lythraceae) Cultivated in Egypt
  Authored by Mohamed Elgindi, Nahla Ayoub, Rola Milad*, Reham Mekky(Egypt)

• Antimicrobial Potential Of Azadirachta Indica Against Pathogenic Bacteria And Fungi
  Authored by Mohammad Asif* (India)

• In-Vitro Anthelmintic Activity of Diplazium esculantum (Retz.) Swiss Rhizome Extract
  Authored by Semwal Amit*, Farswan Mamta Singh (India)

• Herbal Medicine Scenario in India and European Countries
  Authored by Parul Agarwal*, Amreen Fatima and Prem Prakash Singh (India)

• In Vitro Antimicrobial Activity Of Methanolic Extract Of Moringa Olieifera Lam. Fruits
  Authored by Mohammed Abu Sayeed*, Mohammad Shahadat Hossain, Mohammad Ehsanul Hoque Chowdhury and Mohsinul Haque (Bangladesh)

• In-Vitro Thrombolytic and Anti-inflammatory Activity of Swertia Chirata Ethanolic Extract.
  Authored by Mohammad Shahadat Hossain*, Mohammad Ehsanul Hoque Chowdhury, Sumana Das and Imtiaz Uddin Chowdhury. (Bangladesh)

• Pharmacognostical and Priliminary Phytochemical Studies on the Leaf Extract of Ficus Pumila Linn.
  Authored by Jasreet Kaur* (India)

• Formulation and Evaluation of an Herbal Anti-Inflammatory Gel Containing Eupatorium Leaves Extract
  Authored by Arvind Negi*, Nimisha Sharma, Mamta F. Singh (India)

• Aloe Vera: The Miracle Plant Its Medicinal and Traditional Uses in India
  Authored by R. Rajeswari, M. Umadevi*, C. Sharmila Rahale, R.Pushpa, S. Selvavenkadesh, K. P. Sampath Kumar, Debjit Bhowmik (India)

In vitro Membrane Stabilizing Activity, Total Phenolic Content, Cytotoxic, Thrombolytic and Antimicrobial Activities of Calliandra surinamensis (Wall.)

Author: Md. Al Amin Sikder, Md. Shaikhul Millat, Abida Sultana, Mohammad A. Kaisar, and Mohammad A. Rashid

Abstract: Different extractives of leaf of Calliandra surinamensis were evaluated for antimicrobial activity along with membrane stabilizing, thrombolytic and cytotoxic activities. The total phenolic content was also determined and expressed in gallic acid equivalent. The membrane stabilizing activity was assessed by heat and hypotonic solution induced method. In the present studies, the crude methanolic extract (ME) of leaf of C. surinamensis demonstrated strong membrane stabilizing activity, whereas its chloroform (CSF) and pet ether (PESF) soluble fractions revealed moderate membrane stabilizing properties. In brine shrimp bioassay, the aqueous (AQSF) soluble fractions revealed the highest lethality. In antimicrobial screening, the choloroform (CSF) and aqueous (AQSF) soluble fraction demonstrated strong antimicrobial activity against 13 pathogenic microorganisms. The chloroform (CSF) soluble fraction exhibited the highest inhibition against microbial growth having zone of inhibition ranged from 13.0±0.82 mm to 18.3±1.25 mm and maximum zone of inhibition was found 18.3±1.25 mm against Salmonella typhi. In thrombolytic study, the chloroform (CSF) soluble fraction demonstrated mild thrombolytic activity in human blood specimen.

Keyword: Calliandra Surinamensis, Membrane Stabilizing, Thrombolytic, Antimicrobial.

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Investigation of the Pharmacognostical, Phytochemical and Antioxidant Studies of Plant Withania Coagulans Dunal

Author: Chetan Salwaan, Amrinder Singh, Anuj Mittal, Prabhsimran Singh

Abstract: The importance of traditional medicinal plants is increasing now a days because of various advantages over the synthetic drugs. Withania Coagulans dunal was studied for its antioxidant activity. Various physicochemical parameters were studied such as ash value, total ash, acid insoluble ash, water soluble ash, sulphated ash alcohol soluble extractive value etc. Various qualitative phytochemical tests were done for the presence of alkaloids, glycosides, carbohydrates, flavonoids etc. It was observed that 50% ethanol extract of withania coagulans contains carbohydrates, proteins, glycosides, steroids and sterols, anthraquinones and triterpenoids. The anti oxidant activity of Withania coagulans dunal was studied by DPPH and Nitric oxide method and it was observed that it has anti oxidant activity. It showed more activity in DPPH method than Nitric oxide method. Preliminary Phytochemical study of 50% ethanolic extract of the root parts is found to contain carbohydrates, protein, some steroids, anthraquinone, flavonoids, tannin, phenolic compounds and triterpenoids are present. The antioxidant activity was determined and the plant extract showed low activity nitric oxide free radical inhibition method and moderate activity by DPPH method. The activity was compared with rutin and ascorbic acid.

Keyword: Withania Coagulans Dunal, Phytochemical and Antioxidant Studies

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Phytochemical, Ethnobotanical and Pharmacological Profile of Lagenaria siceraria: - A Review

Author: Amit Kumar*, Sangh Partap, Neeraj K. Sharma

Abstract: In traditional systems of medicine, different parts (leaves, stem, flower, root, seeds and even whole plant) of lagenaria siceraria (known as lauki in Hindi), has been used in the ointment for ailment of various diseases throughout India. The fruit of cultivated lagenaria siceraria is the good source of different nutrients components like protein, fat, fibre, carbohydrates, calcium, magnesium. The plant has also been suggested to possess antioxidant activity, laxative, cardioprotective, diuretic, hepatoprotective, hypolipidemic, central nervous system stimulant, anthelmentic, antihypertensive, immunosuppressive analgesic, adaptogenic and free radical scavenging  activity. This work reviews the pharmacological evidence of extracts of plants from the lagenaria siceraria, giving an overview of the most studied biological effects and the known phytochemical composition. Although more studies are necessary, lagenaria siceraria exhibits proven potential to become of important pharmacological interest.

Keyword:Lagenaria Siceraria, Cucurbitaceae, Phytochemistry, Pharmacological Activity.

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