Journal: Journal of Pharmacognosy and Phytochemistry
Author: Mohammad Shahadat Hossain*, Mohammad Ehsanul Hoque Chowdhury, Sumana Das and Imtiaz Uddin Chowdhury
Abstract: Ethanol extract of of Swertia chirata was assessed for its thrombolytic, anti-inflammatory activity and phytochemical screening. In vitro anti-inflammatory activity was evaluated using albumin denaturation. Aspirin was used as a standard drug for the study of anti-inflammatory activity. The ethanol extract of Swertia chirata showed mean inhibition of protein denaturation 45.31±0.000576 whereas, for control group it was found to be 50.00±0.00177. In thrombolytic activity using in vitro clot lysis assay method, the crude ethanol extract was found to have significant, thrombolytic test showed a maximum effect of 40.38% while the standard streptokinase showed 69.35.
